A fire inside a two-story home in Melrose on Tuesday left three people hurt, one of them with serious injuries, according to FDNY. Firefighters responded to the flames on the second floor at 377 E 154th St at around 12:46 a.m. Exclusive video shared with News 12 shows the intense blaze ripping from a second-floor window as smoke billowed into the air. Moments later, firefighters are seen rushing into the home to try and contain the flames. FDNY says as 12-year-old boy and a 17-year-old boy were taken to Lincoln Medical hospital with minor injuries, and a 43-year-old woman was taken to Harlem Hospital with serious life-threatening injuries. Mateo Edwards was visiting family when he came across the chaotic scene. He tells News 12 he spoke with some of the victims and says a family of seven lived inside the home. He detailed the heartbreak expressed by one of the family members. “He was very traumatized. He really didn't want to speak much. He started crying. His wife, like I said, she's in the hospital. The grandkids are in the hospital as well,” said Edwards. 79 emergency crews battled the blaze and put the fire under control at around 1:52 a.m. The Department of Buildings was present at the scene, but it’s unclear the extent of the damage on the homes structure. A fire investigation unit remained at the scene, as FDNY says they’re investigating the cause of the flames.